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How Medication Impacts Your Liver Health

Email sent: Apr 13, 2021 7:59am
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Liver Damage and Medications

While so many people consider over-the-counter medication as an essential part of their overall healthcare, the researchers from the Perelman School of Medicine at the University of Pennsylvania found that the over-the-counter drugs and dietary/herbal supplements are most common causes of liver failure. The researchers have also discovered that 75% of acute liver failure cases caused by the prescription drugs actually resulted from over-the-counter products such as acetaminophen or herbal supplements. Surprisingly, the prescription drugs were found to be a rare cause of acute liver failure.

Paracetamol, NSAIDs and Antibiotics

The liver has an important role in processing and removing drugs from the blood and eliminating them from the body. Normally, a healthy liver does not have any problems with the processing of a reasonable amount of substances and recovering from it. However, when either too many medications are being taken, the body reacts hyper-sensitively to certain substances or when the liver is already damaged, the liver becomes susceptible to damage from drugs. To the liver-damaging medicines particularly belong paracetamol, NSAIDs (nonsteroidal anti-inflammatory drugs), and antibiotics, according to the study. The combination of amoxicillin and clavulanic acid was responsible for 22% of all liver damage cases.

What Is Drug-Induced Liver Injury?

Drug-induced liver injury (DILI) is a very common form of liver damage and accounts for approximately 13% of all cases of acute liver failure in the United States. DILI is a very serious and challenging type of liver disease due to its unpredictable course, difficult diagnosis, and possible mortality risk. Drug-induced liver injury refers to a liver damage caused by the medications, including both prescription and over-the-counter drugs. The liver damage symptoms can be acute (sudden) or appear in a couple of weeks after drug intake. The liver damage can appear in a light and even fatal form. Unspecific symptoms of the drug-induced liver injury make it difficult to indicate disease at the early stages that is why medical help is strictly required for setting a diagnosis.

Amsety´s Tips

Read carefully the directions on the label of your medication and do not exceed the allowed dosing. Make sure to take into account the following important information before taking the medicine:

  • Daily dosing for adults and children and recommended treatment duration.
  • Possible health risks, side effects, and allergic reactions.
  • Usage of the medication in combination with the other drugs and alcohol.
  • Storage requirements.
  • Strictly follow your doctor's prescriptions and never take more medicines than directed.
  • Keep track of the medicines (doses and time) you have to take daily.
  • Do not take any medications longer than it is recommended in the directions or prescribed by the doctor.
  • Store medicines out of reach of children and pets.
Please be safe and take care of yourself whilst we take care of your liver-healthy diet.

Your Amsety Team.
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Please note that we do not provide any medical advice, diagnoses, procedures, tests or therapies on our website. Amsety does not offer any medical diagnosis or treatment advice and our products are not considered to diagnose, treat, cure or prevent any disease. As a liver patient, you should always discuss your diet with your doctor.

 
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