Nature Journal
Nature Journal

Popular preprint servers face closure because of money troubles

Email sent: Feb 13, 2020 1:04pm

Is this your brand on Milled? You can claim it.

What matters in science | 
View this email in your browser Thursday 13 February 2020
Nature Briefing

Hello Nature readers,
Today we learn that popular preprint servers face closure because of money troubles, discover why epidemiologists are concerned that cases of the new coronavirus might be going undetected and hear an argument for a carbon tax to protect tropical forests.

Close up view of a pair of research mice in a glass terrarium at the Jackson Laboratory in Bar Harbor, Maine.
More than 60% of the animals used for science across the EU in 2017 were mice. (Whitney Hayward/Portland Press Herald/Getty)

Tough EU animal-research rules show effect

The use of animals in scientific research seems to be declining in the European Union. The drop follows the introduction seven years ago of legislation designed to reduce the use of animals in research and minimize their suffering. The first report on the state of animal research in the EU since the change says that 9.39 million animals were used for scientific purposes in 2017, compared with 9.59 million in 2015.

Nature | 3 min read

Popular preprint servers face closure

Preprint repositories such as IndiaRxiv, ArabiXiv, AfricArxiv and INA-Rxiv (from Indonesia) boost the visibility of regional science, but finding cash to run them is proving difficult. Some discipline-specific repositories, such as EarthArXiv and MarXiv (for marine-conservation science), are also struggling. At issue are new fees introduced by the non-profit Center for Open Science, based in the United States, which hosts 26 such repositories.

Nature | 5 min read

COVID-19 coronavirus outbreak

Colourized scanning electron microscope image of SARS-CoV-2
This scanning electron microscope image shows SARS-CoV-2, isolated from a patient in the United States, emerging from the surface of cells cultured in the lab. (NIAID-RML/de Wit/Fischer)

Models suggest cases are going undetected

  • Some researchers in China are unhappy with the name announced for the new coronavirus, SARS-CoV-2. The name points to similarities between the evolutionary history of the new virus and that of the virus that causes severe acute respiratory syndrome (SARS). But some scientists worry that the public will make incorrect assumptions about the similarity of the diseases caused by the two viruses. (Nature | continuously updated)
  • Epidemiologists are concerned that cases of the new coronavirus might be going undetected in some places. One model of the virus’s spread, based on flight data, identified 30 countries at high risk of an outbreak. But several of those countries, including Thailand, Vietnam, Cambodia and Malaysia, have reported fewer cases than the model predicts. Indonesia, another country at risk, has yet to report a single case. (Nature | 5 min read)
  • There are four vaccine candidates in development for SARS-CoV-2, says World Health Organization virologist Marie-Paule Kieny. “It’s likely that there will be one or two that will go into human trials in about three to four months from now,” she said. “However, it would take at least 12 to 18 months for a vaccine to become available for wider use.” Doctors in China are also testing a combination of two HIV drugs — lopinavir and ritonavir — as well as a drug called remdesivir, which was originally developed to treat the Ebola virus. (New Scientist | 3 min read)

Click to watch
In this three-minute guide to how scientists are fighting COVID-19, discover the fields of research that are crucial to keeping outbreaks under control: epidemiology, virology and biomedical science. (Nature | 3 min video) ()

Notable quotable

“The specifics of each virus are important, but so is an overarching question: what do you do when large numbers of people arrive wanting care for suspected infections of an unfamiliar disease?”

Infectious-disease physician Nahid Bhadelia reflects on lessons for hospitals learned from the SARS, H1N1 swine flu and Ebola epidemics. (Nature)

Features & opinion

Edgar Torres rides a horse back from the Yorkin River after dropping off a load of plantain.
A tropical forest in the Bribri Indigenous region of Costa Rica. (Ivan Kashinsky/Panos)

Adopt a carbon tax to protect tropical forests

There is a quick, cheap way to lower carbon emissions and protect the more than three-quarters of species that live in the tropics: reduce tropical deforestation. To pay for it, an economist, a conservationist and the environment ministers of Colombia and Costa Rica argue for a levy on fossil fuels. Their analysis shows that, if 12 other countries with tropical forests roll out a carbon tax similar to Colombia’s, they could raise US$1.8 billion each year between them to invest in natural habitats that benefit the climate.

Nature | 10 min read

Irreproducibility is not a sign of failure

The upside of irreproducibility can be found in attempt to measure the precise value of the constant of gravitation (G) — which is still uncertain despite numerous experiments spanning three centuries. When results in the science of measurement cannot be reproduced, argue metrologists Martin Milton and Antonio Possolo, it’s a sign of the scientific method at work — and an opportunity to promote public awareness of the research process.

Questions in biomedicine and the social sciences do not reduce cleanly to the determination of a fundamental constant of nature. But metrology reminds us that irreproducibility should not automatically be seen as a sign of failure, argues a Nature editorial. It can also be an indication that it’s time to rethink our assumptions.

Nature Physics | 9 min read & Nature | 4 min read

Correspondence: your letters to Nature

Romania needs its astronomers back
The Romanian Academy’s outdated regulations discourage researchers who have pursued careers abroad from returning home, writes astronomer Ovidiu Vaduvescu.

China: clamp down on violations of wildlife trade ban
In response to the coronavirus outbreak, China has temporarily banned the transport and sale of wild animals. But people are dodging the law all too easily, write four researchers — creating a disaster for global biodiversity, animal welfare and human health.

A permanent ban might not work in China
Outlawing the sale of wildlife risks fuelling an intractable, uncontrolled and highly priced illegal trade, write four researchers. They say the demand in China for animal parts and game meat needs to be managed through initiatives that discourage consumption, such as education campaigns that aim to discredit ingrained cultural beliefs.

Correspondence is published every week in Nature. For more info on writing one yourself, please see the guidance on (Your feedback on this newsletter is always welcome at, but won’t be considered for publication in Nature.)

Quote of the day

“I have had six decades of experience on both sides of the gun and have been wounded several times by gunfire.”

Former US surgeon-general Richard Carmona — who has also been in the special forces, a homicide detective, a SWAT team member, a combat medic, a paramedic, a registered nurse and a trauma surgeon — writes a heartfelt summation in a special edition of Current Trauma Reports on gun violence.

Watch migrations of swallows and waterfowl sweep up and down the Americas in great waves in these gorgeous visualizations built from citizen-science data by the Cornell Lab of Ornithology.

Keep this newsletter moving in the right direction — please send your feedback to

Flora Graham, senior editor, Nature Briefing

Join our community twitter Facebook

You received this newsletter because you subscribed with the email address: -

Enjoying this newsletter? Please recommend it to a friend or colleague. Use this form to recommend it and be entered to win a Nature 150th anniversary tote bag filled with Nature goodies.
Had enough? Unsubscribe from the Nature Briefing.
Fancy a bit of a read? View our privacy policy.
Forwarded by a friend? Get the Briefing straight to your inbox: subscribe for free.

Nature | The Springer Nature Campus, 4 Crinan Street, London, N1 9XW, United Kingdom

Nature Research, part of Springer Nature.
© 2020 Springer Nature Limited. All rights reserved.

Other emails from Nature Journal

Nature Journal
Feb 21, 2020
AI discovers powerful new antibiotics
Nature Journal
Feb 20, 2020
Coronavirus latest: scientists question case-counting methods
Nature Journal
Feb 19, 2020
Signs that the COVID-19 coronavirus epidemic has peaked are met with caution
Nature Journal
Feb 18, 2020
30 years ago, the iron hypothesis of ice-age cooling instigated an explosion of research
Nature Journal
Feb 17, 2020
Dozens of COVID-19 coronavirus clinical trials take off in China
Nature Journal
Feb 14, 2020
Stunning shots of the most distant object of the Solar System ever imaged up close