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2 in 5: MTHFR gene

Email sent: May 6, 2021 6:07pm
Prevalence of the MTHFR gene mutation
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Rootine Vitamins

The MTHFR gene is involved in the conversion of folate (folic acid and food-derived folates) into the bioactive form, called methylfolate or 5-MTHF. MTHFR plays an extremely important role in a baby's development. Having an adequate amount of folate contributes to healthy neural tube (brain and spine) development during pregnancy.

SNPs in the MTHFR gene can influence folate conversion by altering the structure of the MTHFR enzyme. A gene mutation decreases your bodies ability to convert folic acid into the bioactive form, methylfolate (5-MTHF), meaning your body has less bioactive folate to use for key processes so you may not have adequate folate levels. 40% of the population has at least one mutation in the MTHFR gene. This information is valuable when determining the optimal dose of vitamin B9, a key micronutrient that goes into your Rootine formula. Knowing if you are a carrier of the MTHFR gene could be valuable information in your approach to pregnancy.

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