This is the first study we’re sharing as part of NMN Week. One of the best things about NMN is that we’re still finding out new ways it can help our bodies. This week we’re sharing the newest, most exciting NMN developments with you.
NMN Protects Brain Cells Against Ferroptosis
Background
Ferroptosis is a type of cell death, where iron in the cells oxidises and breaks the cell - think of it like your cells rusting.
It occurs when cells undergo stress - for example at high altitudes - and as part of brain conditions like Alzheimer’s and Parkinson’s Disease.
When ferroptosis occurs in brain cells, it causes issues with thinking clearly.
Scientists wanted to test if NMN could help reverse this.
The Study
Scientists stimulated ferroptosis in the brain cells of mice by putting them in conditions similar to high altitude.
They observed that memory and clear thinking got worse with ferroptosis.
When they applied NMN to the cells, the ferroptosis reversed, the cells became healthy again, and the brain power of the mice improved.
This happened because the NMN boosted NAD+ production in the cells, which in turn led to reduced oxidative stress and better protection for the cells.
What this means for us
This study was conducted in mice, but is really exciting for human longevity.
The use of NMN to protect against ferroptosis and the brain damage it causes could help fight against some of the most devastating brain diseases in humans, including ‘incurable’ conditions like Alzheimer’s and Parkinson’s.