This is the fourth and final we’re sharing as part of NMN Week. One of the best things about NMN is that we’re still finding out new ways it can help our bodies. This week we’re sharing the newest, most exciting NMN developments with you.
Background
Stomach cancer is the fifth most common cancer in the world, with only around 20-38% of sufferers surviving past 5 years.
Before stomach cancer develops, stomach cells can lose their identity, changing to a group of cells known as gastric intestinal metaplasia (GIM).
Studies have shown that reversing GIM can prevent the progression of stomach cancer.
This study looked at what caused GIM in the first place, and how this could be reversed.
The Study
Researchers aimed to recreate GIM in miniature organs known as organoids.
When they had successfully done this, they were able to examine the genetic difference between GIM and healthy stomach cells. They found that NAD+ levels were low in the GIM organoids.
To check these findings, they measured again in actual human GIM tissue, with the same results.
Once they found that NAD+ was low in precancerous cells, they checked if boosting the NAD+ levels back up using NMN could reverse the damage.
They found that NMN successfully reversed GIM.
What this means for us
This study doesn’t just give us insight into how NMN could prevent stomach cancer. The implications are much wider.
The reason that restoring NAD+ in the cells helped them return to normal was that NAD+ helped ‘remind’ the cells what their job was. The mutated stomach cells returned to being stomach cells.
Cells losing their identity is an underlying cause for all cancers.
So NMN might help mitigate many other precancerous tissues in the same way it helped with GIM!
This is the last email in NMN week. We hope you’ve enjoyed learning more about this incredible ingredient. If you want to feel the benefits of NMN first hand, click below.
