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June 14, 2026 4:00am EDT

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Source: McKinsey & Company

1 This specific use of this prescription medication is not approved by the U.S. Food and Drug Administration (FDA). Such use, known as “off-label” use, may be prescribed by a licensed healthcare provider based on their clinical judgment. The safety and effectiveness of medications for off-label uses may not be established by the FDA. This information is for educational purposes only and is not medical advice. Always consult your healthcare provider regarding treatment decisions. Side effects may include (this list is not all inclusive): Nausea, Diarrhea, Abdominal discomfort or cramping, Bloating or gas, decreased appetite, Metallic taste in the mouth, Vitamin B12 deficiency with long-term use, and headache. Black Box Warning: Metformin carries a black box warning for lactic acidosis, a rare but serious condition caused by a buildup of lactic acid in the blood. Lactic acidosis can be life-threatening and requires immediate medical attention. The risk is higher in patients with kidney disease, severe liver disease, dehydration, heavy alcohol use, or certain acute medical conditions.

2 Side effects may include Gastrointestinal discomfort (nausea, bloating, cramping), Headache, Fatigue, Skin flushing, A mild “rotten egg” or sulfur taste in the mouth. Warning: Long-term glutathione use may lead to lower zinc levels. Do not use Glutathione if you have asthma. Glutathione may interact with certain medications, such as chemotherapy drugs, potentially affecting their effectiveness. Not recommended for use with patients receiving chemotherapy or those with G6PD deficiency. Those with sulfur allergy should not use this product.

3 Do not use NAD+ if you have active cancer, a history of cancer, are undergoing a work-up for suspected cancer. You should also avoid NAD+ if you do not tolerate stimulating supplements well or are sensitive to flushing.


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Supplements that reflect our commitment to you

Wisp's longevity suite is built with women's biology in mind

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